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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Lapuleucel-T (Code C2057)

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Terms & Properties

Preferred Name: Lapuleucel-T

Definition: A cell-based vaccine targets tumors expressing the HER2/neu marker. HER-2/neu is a growth factor receptor, and its overexpression has been associated with a number of cancers including breast, ovarian, colon and lung cancers. APC8024 comprise of autologous antigen-presenting peripheral blood mononuclear cells (APCs) that have been exposed to HER2/neu protein and can be administered to the patient. These cells may stimulate an antitumor T-cell response to cancer cells expressing HER2/neu. (NCI04)

Display Name: Lapuleucel-T

Label: Lapuleucel-T

NCI Thesaurus Code: C2057 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1515856  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
APC 8024

External Source Codes: 
PDQ Closed Trial Search ID 735849
PDQ Open Trial Search ID 735849 (check for NCI PDQ open clinical trial info)
UMLS CUI C1515856

Other Properties:
     Name Value (qualifiers indented underneath)
code C2057
Contributing_Source CTRP
Legacy_Concept_Name APC_8024
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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