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Version: 17.06d (Release date: 2017-06-26)
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Girentuximab (Code C1960)

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Terms & Properties

Preferred Name: Girentuximab

Definition: A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, monoclonal antibody G250 (mAb G250) may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents. (NCI05)

Display Name: Girentuximab

Label: Girentuximab

NCI Thesaurus Code: C1960 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0540128  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
cG250
Chimeric Monoclonal Antibody cG250
Girentuximab
GIRENTUXIMAB
MoAb G250
Monoclonal Antibody G250
Rencarex
WX-G250

External Source Codes: 
CAS Registry Number 916138-87-9 (see NLM ChemIDplus info)
FDA UNII Code 539B57DFJF
PDQ Closed Trial Search ID 373829
PDQ Open Trial Search ID 373829 (check for NCI PDQ open clinical trial info)
UMLS CUI C0540128

Other Properties:
     Name Value (qualifiers indented underneath)
code C1960
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Monoclonal_Antibody_G-250
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1960

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