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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Interferon Alfa-2b (Code C1953)

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Terms & Properties

Preferred Name: Recombinant Interferon Alfa-2b

Definition: A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.

NCI-GLOSS Definition: A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular lymphoma. It is a form of interferon alfa (a substance normally made by cells of the immune system) that is made in the laboratory. It is a type of biological response modifier.

Display Name: Recombinant Interferon Alfa-2b

Label: Recombinant Interferon Alfa-2b

NCI Thesaurus Code: C1953 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0021735  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Heberon Alfa
IFN alpha-2B
Interferon Alfa-2B
interferon alfa-2b
Interferon alfa 2b
Interferon Alpha-2b
Intron A
Recombinant Interferon Alfa-2b
recombinant interferon alfa-2b
Sch 30500

External Source Codes: 
CAS Registry Number 98530-12-2 (see NLM ChemIDplus info)
CAS Registry Number 99210-65-8 (see NLM ChemIDplus info)
FDA UNII Code 43K1W2T1M6
NSC Code 377523 (see NCI DTP info)
PDQ Closed Trial Search ID 462279
PDQ Open Trial Search ID 462279 (check for NCI PDQ open clinical trial info)
UMLS CUI C0021735

Other Properties:
     Name Value (qualifiers indented underneath)
code C1953
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Recombinant_Interferon_Alfa-2b
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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