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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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NM-3 (Code C1888)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: NM-3

Definition: An orally bioavailable antiangiogenic isocoumarin with potential antineoplastic activity. NM-3 inhibits vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby inhibiting endothelial cell proliferation. This agent also induces apoptosis by a mechanism involving reactive oxygen species. (NCI04)

Label: NM-3

NCI Thesaurus Code: C1888 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1122058  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
NM-3

External Source Codes: 
PDQ Closed Trial Search ID 355804
PDQ Open Trial Search ID 355804 (check for NCI PDQ open clinical trial info)
UMLS CUI C1122058

Other Properties:
     Name Value (qualifiers indented underneath)
code C1888
Legacy_Concept_Name NM-3
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1888

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