skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 16.11d (Release date: 2016-11-28)
SearchBox Top
SearchBox Bottom
Ursodiol (Code C1818)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Ursodiol

Definition: A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract.

NCI-GLOSS Definition: A drug that is used to dissolve gallstones in people who can't have surgery to remove them. It is also being studied in the prevention of colorectal cancer. Ursodiol belongs to the family of drugs called anticholelithics.

Display Name: Ursodiol

Label: Ursodiol

NCI Thesaurus Code: C1818 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0042105  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid
Actigall
Deursil
UDCA
URSO
Ursodeoxycholic Acid
Ursodeoxycholic acid
Ursodiol
URSODIOL
ursodiol

External Source Codes: 
CAS Registry Number 128-13-2 (see NLM ChemIDplus info)
FDA UNII Code 724L30Y2QR
ChEBI ID CHEBI:9907 (see ChEBI info)
NSC Code 657950 (see NCI DTP info)
NSC Code 683769 (see NCI DTP info)
PDQ Closed Trial Search ID 306453
PDQ Open Trial Search ID 306453 (check for NCI PDQ open clinical trial info)
UMLS CUI C0042105

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Gallstone disolution; Primary biliary cirrhosis
Chemical_Formula C24H40O4
code C1818
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Ursodiol
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1818

Mainbox Bottom