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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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Soy Protein Isolate (Code C1803)

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Terms & Properties

Preferred Name: Soy Protein Isolate

Definition: A dietary protein isolated from soybeans that contains isoflavone phytoestrogens. Soy protein isolate has been shown to reduce tumor incidence and growth in some animal studies, possibly by modulating estrogen metabolism, reducing tumor cell proliferation, and inducing tumor cell apoptosis. Soy protein isolate may also inhibit endothelial cell proliferation. Isoflavone phytoestrogens display mild estrogen-like activities which may regulate hormone balance and reduce the risks of breast cancer, heart disease, and osteoporosis. (NCI04)

Display Name: Soy Protein Isolate

Label: Soy Protein Isolate

NCI Thesaurus Code: C1803 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0677666  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Soy Protein Isolate
Soybean Protein Isolate

External Source Codes: 
CAS Registry Number 9010-10-0 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 42493
PDQ Open Trial Search ID 42493 (check for NCI PDQ open clinical trial info)
UMLS CUI C0677666

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Heart disease prevention; hyperlipidemia; menopausal symptoms
code C1803
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Soy_Protein_Isolate
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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