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Version: 16.11d (Release date: 2016-11-28)
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Celecoxib (Code C1728)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Celecoxib

Definition: A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.

NCI-GLOSS Definition: A drug that reduces pain. Celecoxib belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is being studied in the prevention of cancer.

Display Name: Celecoxib

Label: Celecoxib

NCI Thesaurus Code: C1728 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0538927  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-
Celebrex
Celecoxib
CELECOXIB
celecoxib
SC-58635
YM 177

External Source Codes: 
CAS Registry Number 169590-42-5 (see NLM ChemIDplus info)
FDA UNII Code JCX84Q7J1L
ChEBI ID CHEBI:41423 (see ChEBI info)
NSC Code 719627 (see NCI DTP info)
PDQ Closed Trial Search ID 43023
PDQ Open Trial Search ID 43023 (check for NCI PDQ open clinical trial info)
UMLS CUI C0538927

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Acute pain; Familial adenomatous polyposis; Primary dysmenorrhea; Osteoarthritis; Rheumatoid arthritis
Chemical_Formula C17H14F3N3O2S
code C1728
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Celecoxib
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1728

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