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Version: 17.12d (Release date: 2017-12-26)
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Caspofungin Acetate (Code C1724)

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Terms & Properties

Preferred Name: Caspofungin Acetate

Definition: The acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.

NCI-GLOSS Definition: A drug used to prevent or treat infections caused by a fungus (a type of microorganism). It belongs to the family of drugs called antifungal agents.

Display Name: Caspofungin Acetate

Label: Caspofungin Acetate

NCI Thesaurus Code: C1724 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0935942  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Caspofungin Acetate
caspofungin acetate

External Source Codes: 
CAS Registry Number 179463-17-3 (see NLM ChemIDplus info)
ChEBI ID CHEBI:59900 (see ChEBI info)
PDQ Closed Trial Search ID 38182
PDQ Open Trial Search ID 38182 (check for NCI PDQ open clinical trial info)
UMLS CUI C0935942

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C52H88N10O15.2C2H4O2
code C1724
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Caspofungin_Acetate
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  


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