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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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Staphylococcus aureus Protein A (Code C17166)

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Terms & Properties

Preferred Name: Staphylococcus aureus Protein A

Definition: A protein that resides in the microbial wall of staphylococcus aureus and interferes with opsonization by binding to the Fc portion of immunoglobulin. The protein has a deleterious effect on the epithelial cells that line the respiratory tract, and plays a role in the induction of pneumonia. Protein A also initiates polymorphonuclear cell migration into airway passages via TNFR1 activation.

Label: Staphylococcus aureus Protein A

NCI Thesaurus Code: C17166 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0038164  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
S. aureus protein A
Staph. Protein A
Staphylococcus aureus Protein A

External Source Codes: 
PDQ Closed Trial Search ID 39057
PDQ Open Trial Search ID 39057 (check for NCI PDQ open clinical trial info)
UMLS CUI C0038164

Other Properties:
     Name Value (qualifiers indented underneath)
code C17166
Legacy_Concept_Name Staphylococcus_aureus_Protein-A
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Biologically Active Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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