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Version: 17.06d (Release date: 2017-06-26)
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Pentetic Acid Calcium (Code C1710)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Pentetic Acid Calcium

Definition: The calcium salt of pentetic acid, a synthetic chelating agent related to the chelating agent ethylenediaminetetraacetic acid (EDTA). Pentetic acid chelates with the metallic radioisotopic moieties of unbound, extracellular radioimmunotherapeutic agents, resulting in higher specific tumor cell binding of radioimmunotherapeutic agents; this results in improved tumor cell radiocytotoxicity and the sparing of normal cells and tissues from the radiocytotoxic effects of these agents.

NCI-GLOSS Definition: A drug that protects healthy tissues from the toxic effects of anticancer drugs.

Display Name: Pentetic Acid Calcium

Label: Pentetic Acid Calcium

NCI Thesaurus Code: C1710 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C4048602  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Ca-DTPA
Calcium-DTPA
Calcium DTPA
Calcium Pentetic Acid
Pentetic Acid Calcium
pentetic acid calcium

External Source Codes: 
CAS Registry Number 2531-75-1 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 42562
PDQ Open Trial Search ID 42562 (check for NCI PDQ open clinical trial info)
UMLS CUI C4048602

Other Properties:
     Name Value (qualifiers indented underneath)
code C1710
Contributing_Source CTRP
Legacy_Concept_Name Pentetic_Acid_Calcium
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1710

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