skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Voriconazole (Code C1707)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Voriconazole

Definition: A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04)

NCI-GLOSS Definition: A drug that treats infections caused by fungi.

Display Name: Voriconazole

Label: Voriconazole

NCI Thesaurus Code: C1707 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0393080  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
Vfend
Voriconazole
VORICONAZOLE
voriconazole

External Source Codes: 
CAS Registry Number 137234-62-9 (see NLM ChemIDplus info)
FDA UNII Code JFU09I87TR
ChEBI ID CHEBI:10023 (see ChEBI info)
PDQ Closed Trial Search ID 42690
PDQ Open Trial Search ID 42690 (check for NCI PDQ open clinical trial info)
UMLS CUI C0393080

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Aspergillosis, invasive; Esophageal candidiasis; Fungal infections, non-aspergillosis
Chemical_Formula C16H14F3N5O
code C1707
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Voriconazole
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1707

Mainbox Bottom