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Version: 17.12d (Release date: 2017-12-26)
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Indinavir Sulfate (Code C1662)

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Terms & Properties

Preferred Name: Indinavir Sulfate

Definition: A synthetic antiviral agent. Indinavir selectively binds to the active site of human immunodeficiency virus (HIV) protease and inhibits its activity, preventing the protease-mediated cleavage of gag-pol viral polyproteins; as a result immature, noninfectious virions are produced.

Display Name: Indinavir Sulfate

Label: Indinavir Sulfate

NCI Thesaurus Code: C1662 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0700483  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
D-erythro-Pentonamide, 2,3,5-trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-, monohydrate, (1(1S,2R),5(S))-, sulfate (1:1) (salt)
Indinavir Sulfate

External Source Codes: 
CAS Registry Number 157810-81-6 (see NLM ChemIDplus info)
FDA UNII Code 771H53976Q
ChEBI ID CHEBI:5899 (see ChEBI info)
NSC Code 697197 (see NCI DTP info)
PDQ Closed Trial Search ID 42594
PDQ Open Trial Search ID 42594 (check for NCI PDQ open clinical trial info)
UMLS CUI C0700483

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C36H47N5O4.H2SO4
code C1662
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Indinavir
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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