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National Cancer Institute
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Version: 17.08d (Release date: 2017-08-28)
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Tecogalan Sodium (Code C1605)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Tecogalan Sodium

Definition: A sulfated polysaccharide isolated from various Arthrobacter bacterial species. Possessing potential antiangiogenic and antineoplastic properties, tecogalan binds to basic fibroblast growth factor (bFGF), thereby preventing bFGF from binding to its receptors. Disruption of this receptor binding results in the inhibition of bFGF-stimulated endothelial cell growth, proliferation, and migration. (NCI04)

Label: Tecogalan Sodium

NCI Thesaurus Code: C1605 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0212199  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Sulfated Polysaccharide Tecogalan DS-4152
Tecogalan Sodium

External Source Codes: 
PDQ Closed Trial Search ID 42149
PDQ Open Trial Search ID 42149 (check for NCI PDQ open clinical trial info)
UMLS CUI C0212199

Other Properties:
     Name Value (qualifiers indented underneath)
code C1605
Legacy_Concept_Name Tecogalan_Sodium
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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