|Levofloxacin (Code C1586)|
|Terms & Properties|
Preferred Name: Levofloxacin
Definition: A broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
NCI-GLOSS Definition: A substance used to treat bacterial infections. It belongs to the family of drugs called quinolone antibiotics.
Display Name: Levofloxacin
NCI Metathesaurus Link: C0282386 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|CAS Registry Number||138199-71-0 (see NLM ChemIDplus info)|
|FDA UNII Code||6GNT3Y5LMF|
|PDQ Closed Trial Search ID||37941|
|PDQ Open Trial Search ID||37941 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|