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Version: 16.10e (Release date: 2016-10-31)
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Benzydamine Hydrochloride (Code C1581)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Benzydamine Hydrochloride

Definition: An indazole non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic, and anti-edema properties. Unlike other NSAIDs, benzydamine hydrochloride does not inhibit cyclooxygenases (COX) but stabilizes membranes, resulting in local anesthesia; inhibits the production of pro-inflammatory cytokines; inhibits the generation of reactive oxygen species by neutrophils; inhibits leukocyte aggregation and adhesion; and exhibits antimicrobial properties. (NCI04)

Label: Benzydamine Hydrochloride

NCI Thesaurus Code: C1581 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1511108  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BENZYDAMINE HYDROCHLORIDE
Benzydamine Hydrochloride
Difflam
Tantum

External Source Codes: 
CAS Registry Number 132-69-4 (see NLM ChemIDplus info)
FDA UNII Code K2GI407R4Q
PDQ Closed Trial Search ID 42672
PDQ Open Trial Search ID 42672 (check for NCI PDQ open clinical trial info)
UMLS CUI C1511108

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Radiation-induced oral mucositis
Chemical_Formula C19H23N3O.HCl
code C1581
Contributing_Source FDA
Legacy_Concept_Name Benzydamine_Hydrochloride
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1581

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