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Version: 17.10e (Release date: 2017-10-30)
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Benzydamine Hydrochloride (Code C1581)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Benzydamine Hydrochloride

Definition: An indazole non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic, and anti-edema properties. Unlike other NSAIDs, benzydamine hydrochloride does not inhibit cyclooxygenases (COX) but stabilizes membranes, resulting in local anesthesia; inhibits the production of pro-inflammatory cytokines; inhibits the generation of reactive oxygen species by neutrophils; inhibits leukocyte aggregation and adhesion; and exhibits antimicrobial properties. (NCI04)

Label: Benzydamine Hydrochloride

NCI Thesaurus Code: C1581 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0282070  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Benzydamine Hydrochloride

External Source Codes: 
CAS Registry Number 132-69-4 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 42672
PDQ Open Trial Search ID 42672 (check for NCI PDQ open clinical trial info)
UMLS CUI C0282070

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Radiation-induced oral mucositis
Chemical_Formula C19H23N3O.HCl
code C1581
Contributing_Source FDA
Legacy_Concept_Name Benzydamine_Hydrochloride
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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