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Version: 17.06d (Release date: 2017-06-26)
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Rhenium Re-186 Hydroxyethylidene Diphosphonate (Code C1562)

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Terms & Properties

Preferred Name: Rhenium Re-186 Hydroxyethylidene Diphosphonate

Definition: An synthetic compound containing the organic phosphonate hydroxyethylidene diphosphonate (HEDP) labeled with the radioisotope rhenium Re 186. Re-186 hydroxyethylidene diphosphonate binds to hydroxyapatite in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. Re-186 is a beta emitter with a short half-life, a radioisotope profile that provides localized antitumor radiocytotoxicity while sparing extramedullary bone marrow tissues.

Label: Rhenium Re-186 Hydroxyethylidene Diphosphonate

NCI Thesaurus Code: C1562 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0280809  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
186Re-Etidronate
Re-186 HEDP
Re-186 Hydroxyethylidene Diphosphonate
Re 186 Hydroxyethylidene Diphosphonate
Rhenium-186 HEDP
Rhenium Re-186 Hydroxyethylidene Diphosphonate
Rhenium Re 186 Etidronate

External Source Codes: 
CAS Registry Number 140709-07-5 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 41205
PDQ Open Trial Search ID 41205 (check for NCI PDQ open clinical trial info)
UMLS CUI C0280809

Other Properties:
     Name Value (qualifiers indented underneath)
code C1562
Legacy_Concept_Name Re_186_Hydroxyethylidene_Diphosphonate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1562

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