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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Edrecolomab (Code C1554)

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Terms & Properties

Preferred Name: Edrecolomab

Definition: A murine monoclonal IgG2a antibody to tumor-associated epithelial cell adhesion molecule (EpCAM, or 17-1A) antigen. Edrecolomab attaches to EpCAM, a human cell surface glycoprotein that is found on normal epithelial cells and some tumor cells, such as those of colon and breast carcinomas. Upon binding, this agent recruits the body's immune effector cells, which may exhibit antitumor cytotoxicity. (NCI04)

NCI-GLOSS Definition: A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells.

Display Name: Edrecolomab

Label: Edrecolomab

NCI Thesaurus Code: C1554 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0279218  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Immunoglobulin G2A (Mouse Monoclonal 17-1A Gamma-Chain Anti-Human Colon Cancer Tumor-Associated Antigen), Disulfide With Mouse Monoclonal 17-1A Light Chain, Dimer
MOAB 17-1A
Monoclonal Antibody 17-1A

External Source Codes: 
CAS Registry Number 156586-89-9 (see NLM ChemIDplus info)
NSC Code 377963 (see NCI DTP info)
PDQ Closed Trial Search ID 39352
PDQ Open Trial Search ID 39352 (check for NCI PDQ open clinical trial info)
UMLS CUI C0279218

Other Properties:
     Name Value (qualifiers indented underneath)
code C1554
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Edrecolomab
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: Yes  


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