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Version: 17.06d (Release date: 2017-06-26)
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Arcitumomab (Code C1494)

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Terms & Properties

Preferred Name: Arcitumomab

Definition: A murine IgG monoclonal Fab' fragment antibody directed against carcinoembryonic antigen (CEA), a protein that is overexpressed by many tumor cell types. For tumors that overexpress CEA, technetium-99m labeled arcitumomab may be used as an adjunct diagnostic imaging tool to obtain prognostic information following resection and to monitor for recurrent disease. (NCI04)

Label: Arcitumomab

NCI Thesaurus Code: C1494 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0758542  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Immunoglobulin G 1 (mouse monoclonal IMMU-4 Fab' fragment gamma-chain anti-human antigen CEA), disulfide with mouse Monoclonal IMMU-4 Light Chain

External Source Codes: 
CAS Registry Number 154361-48-5 (see NLM ChemIDplus info)
FDA UNII Code 79T6JRG308
PDQ Closed Trial Search ID 42612
PDQ Open Trial Search ID 42612 (check for NCI PDQ open clinical trial info)
UMLS CUI C0758542

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Colorectal carcinoma and medullary thyroid carcinoma detection
code C1494
Contributing_Source FDA
Legacy_Concept_Name Arcitumomab
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  


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