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Version: 17.12d (Release date: 2017-12-26)
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QS21 (Code C1478)

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Terms & Properties

Preferred Name: QS21

Definition: A purified, natural saponin isolated from the soapbark tree Quillaja saponaria Molina with potential immunoadjuvant activity. When co-administered with vaccine peptides, QS21 may increase total antitumoral vaccine-specific antibody responses and cytotoxic T-cell responses.

NCI-GLOSS Definition: A substance from plants that is being studied together with vaccine therapy for its ability to improve the way the immune system responds to disease. It belongs to the family of drugs called saponin adjuvants.

Display Name: QS21

Label: QS21

NCI Thesaurus Code: C1478 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0211668  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
QS-21 Adjuvant
Stimulon QS-21 Adjuvant

External Source Codes: 
CAS Registry Number 141256-04-4 (see NLM ChemIDplus info)
NSC Code 679689 (see NCI DTP info)
PDQ Closed Trial Search ID 41579
PDQ Open Trial Search ID 41579 (check for NCI PDQ open clinical trial info)
UMLS CUI C0211668

Other Properties:
     Name Value (qualifiers indented underneath)
code C1478
Contributing_Source CTRP
Legacy_Concept_Name QS21
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: Yes  


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