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Version: 16.11d (Release date: 2016-11-28)
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Ziconotide (Code C1475)

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Terms & Properties

Preferred Name: Ziconotide

Definition: A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain.

NCI-GLOSS Definition: A drug used in the treatment of chronic pain.

Label: Ziconotide

NCI Thesaurus Code: C1475 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0211011  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Prialt
SNX-111
SNX 111
ZICONOTIDE
Ziconotide
ziconotide

External Source Codes: 
CAS Registry Number 107452-89-1 (see NLM ChemIDplus info)
FDA UNII Code 7I64C51O16
PDQ Closed Trial Search ID 42866
PDQ Open Trial Search ID 42866 (check for NCI PDQ open clinical trial info)
UMLS CUI C0211011

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C102H172N36O32S7
code C1475
Contributing_Source FDA
Legacy_Concept_Name Ziconotide
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1475

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