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Version: 17.06d (Release date: 2017-06-26)
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Enoxaparin (Code C1452)

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Terms & Properties

Preferred Name: Enoxaparin

Definition: A low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. (NCI04)

NCI-GLOSS Definition: A drug used to prevent blood clots. It belongs to the family of drugs called anticoagulants.

Display Name: Enoxaparin

Label: Enoxaparin

NCI Thesaurus Code: C1452 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0206460  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
CAS Registry Number 9005-49-6 (see NLM ChemIDplus info)
ChEBI ID CHEBI:28304 (see ChEBI info)
NSC Code 728167 (see NCI DTP info)
PDQ Closed Trial Search ID 37880
PDQ Open Trial Search ID 37880 (check for NCI PDQ open clinical trial info)
UMLS CUI C0206460

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula (C14H18NO11)n.C14H18NO11.C12H17NO12S.(C12H16NO13S)n.C12H15NO13S.Na.H.5HO3S
code C1452
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Enoxaparin
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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