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Version: 17.06d (Release date: 2017-06-26)
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Perflubron (Code C1422)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Perflubron

Definition: A synthetic radiopaque liquid form of perfluorooctyl bromide. Used as a contrast agent for magnetic resonance imaging (MRI), perflubron is also used as a liquid ventilation agent to improve pulmonary gas exchange and lung compliance and may be used in surgery to reduce or eliminate the need for donor blood. Ventilation with perfluorocarbon fluid improves lung function in conditions involving surfactant deficiency and dysfunction, including respiratory distress syndrome and adult respiratory distress syndrome. (NCI04)

Label: Perflubron

NCI Thesaurus Code: C1422 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0162922  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Imagent GI
PERFLUBRON
Perflubron
Perfluorooctylbromide
PFOB

External Source Codes: 
CAS Registry Number 423-55-2 (see NLM ChemIDplus info)
FDA UNII Code Q1D0Q7R4D9
ChEBI ID CHEBI:38803 (see ChEBI info)
PDQ Closed Trial Search ID 41963
PDQ Open Trial Search ID 41963 (check for NCI PDQ open clinical trial info)
UMLS CUI C0162922

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C8BrF17
code C1422
Contributing_Source FDA
Legacy_Concept_Name Perflubron
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1422

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