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Version: 17.06d (Release date: 2017-06-26)
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Goserelin Acetate (Code C1417)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Goserelin Acetate

Definition: The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)

Display Name: Goserelin Acetate

Label: Goserelin Acetate

NCI Thesaurus Code: C1417 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0700476  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
D-Ser(bu(t))(6)azgly(10)-LHRH Acetate
Goserelin Acetate
GOSERELIN ACETATE
ZDX
Zoladex

External Source Codes: 
CAS Registry Number 65807-02-5 (see NLM ChemIDplus info)
FDA UNII Code 6YUU2PV0U8
NSC Code 606864 (see NCI DTP info)
PDQ Closed Trial Search ID 40224
PDQ Open Trial Search ID 40224 (check for NCI PDQ open clinical trial info)
UMLS CUI C0700476

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Breast Carcinoma; Prostate Carcinoma; Endometriosis
Chemical_Formula C59H84N18O14.C2H4O2
code C1417
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Goserelin_Acetate
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1417

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