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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Human Stem Cell Factor (Code C1410)

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Terms & Properties

Preferred Name: Recombinant Human Stem Cell Factor

Definition: A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures.

Label: Recombinant Human Stem Cell Factor

NCI Thesaurus Code: C1410 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1526982  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
c-Kit Ligand
Mast Cell Growth Factor
Recombinant Human Stem Cell Factor
Steel Factor

External Source Codes: 
PDQ Closed Trial Search ID 41929
PDQ Open Trial Search ID 41929 (check for NCI PDQ open clinical trial info)
UMLS CUI C1526982

Other Properties:
     Name Value (qualifiers indented underneath)
code C1410
Legacy_Concept_Name Therapeutic_Stem_Cell_Factor
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: Yes  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1410

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