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Version: 17.06d (Release date: 2017-06-26)
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Isosulfan Blue (Code C1386)

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Terms & Properties

Preferred Name: Isosulfan Blue

Definition: A synthetic visual lymphatic imaging agent. Injected into the periphery of the tumor site, isosulfan blue localizes to the lymphatic system and aids in the surgical identification of tumor sentinel nodes which stain blue. (NCI04)

NCI-GLOSS Definition: A dye made in the laboratory that helps identify the sentinel lymph node (the first lymph node that cancer spreads to from a primary tumor). Isosulfan blue is injected at the edge of a tumor and travels through the lymph fluid to lymph nodes near the tumor. The sentinel lymph node is identified by removing lymph nodes that are stained with the blue dye and looking for cancer cells under a microscope.

Display Name: Isosulfan Blue

Label: Isosulfan Blue

NCI Thesaurus Code: C1386 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0063908  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Isosulfan Blue
isosulfan blue
ISOSULFAN BLUE
Lymphazurin
N-[4-[(4-(diethylamino)phenyl)(2,5-disulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-ethanaminium hydroxide

External Source Codes: 
CAS Registry Number 68238-36-8 (see NLM ChemIDplus info)
FDA UNII Code 39N9K8S2A4
PDQ Closed Trial Search ID 42639
PDQ Open Trial Search ID 42639 (check for NCI PDQ open clinical trial info)
UMLS CUI C0063908

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Diagnostic imaging
Chemical_Formula C27H31N2O6S2.Na
code C1386
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Isosulfan_Blue
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1386

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