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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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PEG-interleukin-2 (Code C1304)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: PEG-interleukin-2

Definition: A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with antineoplastic activity. PEG-interleukin-2 induces natural killer (NK) cell activity and the production of interferon-gamma (IFN-gamma), and enhances T cell-mediated cytotoxicity. Pegylation of IL-2 protects the cytokine from degradation. (NCI04)

Label: PEG-interleukin-2

NCI Thesaurus Code: C1304 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0083036  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Polyethylene Glycol-Modified Recombinant Interleukin-2

External Source Codes: 
PDQ Closed Trial Search ID 39577
PDQ Open Trial Search ID 39577 (check for NCI PDQ open clinical trial info)
UMLS CUI C0083036

Other Properties:
     Name Value (qualifiers indented underneath)
code C1304
Legacy_Concept_Name PEG-interleukin-2
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  


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