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Version: 17.06d (Release date: 2017-06-26)
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Thymopentin (Code C1294)

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Terms & Properties

Preferred Name: Thymopentin

Definition: A synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties. Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle. (NCI04)

Label: Thymopentin

NCI Thesaurus Code: C1294 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0080225  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Immunox
Mepentil
N-(N-(N-(N(2)-L-Arginyl-L-Lysyl)-L-alpha-Aspartyl)-L-Valyl)-L-Tyrosine
N-[N-[N-(N{2}-L-Arginyl-L-lysyl)-L-alpha-aspartyl]-L-valyl]-L-tyrosine
ORF-15244
Sintomodulina
Thymopentin
THYMOPENTIN
Timunox

External Source Codes: 
CAS Registry Number 69558-55-0 (see NLM ChemIDplus info)
FDA UNII Code O3Y80ZF13F
NSC Code 645363 (see NCI DTP info)
PDQ Closed Trial Search ID 41655
PDQ Open Trial Search ID 41655 (check for NCI PDQ open clinical trial info)
UMLS CUI C0080225

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C30H49N9O9
code C1294
Contributing_Source FDA
Legacy_Concept_Name Thymopentin
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1294

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