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Version: 17.12d (Release date: 2017-12-26)
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Ormaplatin (Code C1250)

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Terms & Properties

Preferred Name: Ormaplatin

Definition: A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity.

Label: Ormaplatin

NCI Thesaurus Code: C1250 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0076329  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Platinum, tetrachloro(1,2-cyclohexanediamine-N,N')-, (OC-6-22-(trans))-
tetrachloro(1,2-cyclohexanediamine-N,N')-, (OC-6-22-(trans))Platinum

External Source Codes: 
CAS Registry Number 62816-98-2 (see NLM ChemIDplus info)
NSC Code 363812 (see NCI DTP info)
PDQ Closed Trial Search ID 41211
PDQ Open Trial Search ID 41211 (check for NCI PDQ open clinical trial info)
UMLS CUI C0076329

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C6H14N2.4Cl.Pt
code C1250
Contributing_Source FDA
Legacy_Concept_Name Ormaplatin
Semantic_Type Inorganic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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