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Version: 17.06d (Release date: 2017-06-26)
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Terephthalamidine (Code C1245)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Terephthalamidine

Definition: A derivative of the phthalanilide compounds. Terephthalamidine belongs to a family of compounds which appear to reversibly bind to the minor groove of the DNA double helix but not intercalate DNA. This agent also has been suggested to form ionic complexes with many biological components in vitro, including nucleic acids, proteins and lipids.

Label: Terephthalamidine

NCI Thesaurus Code: C1245 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0076116  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1,4-Benzenedicarboximidamide
Terephthalamidine

External Source Codes: 
CAS Registry Number 15411-54-8 (see NLM ChemIDplus info)
NSC Code 57155 (see NCI DTP info)
PDQ Closed Trial Search ID 41351
PDQ Open Trial Search ID 41351 (check for NCI PDQ open clinical trial info)
UMLS CUI C0076116

Other Properties:
     Name Value (qualifiers indented underneath)
code C1245
Legacy_Concept_Name Terephthalamidine
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1245

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