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Version: 17.06d (Release date: 2017-06-26)
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Retinyl Acetate (Code C1216)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Retinyl Acetate

Definition: A naturally-occurring fatty acid ester form of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Retinyl acetate binds to and activates retinoid receptors, inducing cell differentiation and decreasing cell proliferation. This agent also inhibits carcinogen-induced neoplastic transformation in some cancer cell types and exhibits immunomodulatory properties. (NCI04)

Label: Retinyl Acetate

NCI Thesaurus Code: C1216 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0073109  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Retinol Acetate
Retinyl Acetate
Retinyl acetate
Vitamin A, acetate
vitamin A acetate
VITAMIN A ACETATE

External Source Codes: 
CAS Registry Number 127-47-9 (see NLM ChemIDplus info)
FDA UNII Code 3LE3D9D6OY
ChEBI ID CHEBI:32095 (see ChEBI info)
NSC Code 122760 (see NCI DTP info)
NSC Code 122045 (see NCI DTP info)
PDQ Closed Trial Search ID 40313
PDQ Open Trial Search ID 40313 (check for NCI PDQ open clinical trial info)
UMLS CUI C0073109

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Dietary supplement; vitamin A deficiency
Chemical_Formula C22H32O2
code C1216
Contributing_Source FDA
Legacy_Concept_Name Retinyl_Acetate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1216

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