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Version: 17.06d (Release date: 2017-06-26)
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Resveratrol (Code C1215)

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Terms & Properties

Preferred Name: Resveratrol

Definition: A phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose- and time-dependent manner. (NCI05)

NCI-GLOSS Definition: A substance found in the skins of grapes and in certain other plants, fruits, and seeds. It is made by various plants to help defend against invading fungi, stress, injury, infection, and too much sunlight. It is being studied in the prevention of cancer and heart disease. It is a type of antioxidant and a type of polyphenol.

Display Name: Resveratrol

Label: Resveratrol

NCI Thesaurus Code: C1215 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0073096  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
3,4',5-Stilbenetriol
Resveratrol
resveratrol
RESVERATROL

External Source Codes: 
CAS Registry Number 501-36-0 (see NLM ChemIDplus info)
FDA UNII Code Q369O8926L
ChEBI ID CHEBI:45713 (see ChEBI info)
ChEBI ID CHEBI:27881 (see ChEBI info)
NSC Code 327430 (see NCI DTP info)
PDQ Closed Trial Search ID 405819
PDQ Open Trial Search ID 405819 (check for NCI PDQ open clinical trial info)
UMLS CUI C0073096

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C14H12O3
code C1215
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Resveratrol
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1215

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