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Version: 17.06d (Release date: 2017-06-26)
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Pentamethylmelamine (Code C1189)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Pentamethylmelamine

Definition: A principal metabolite of hexamethylmelamine with antineoplastic activity. Pentamethylmelamine alkylates DNA and other macromolecules and forms DNA intrastrand and DNA-protein crosslinks, thereby preventing DNA replication. (NCI04)

Label: Pentamethylmelamine

NCI Thesaurus Code: C1189 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0070302  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1,3,5-Triazine-2,4,6-triamine, N,N,N',N', N''-pentamethyl-, monohydrochloride (9CI)
Melamine, N2,N2,N4,N4,N6-pentamethyl-, monohydrochloride
melamine, N2,N2,N4,N4,N6-pentamethyl-, monohydrochloride
Pentamethylmelamine monoHCl
Pentamethylmelamine MonoHCl
Pentamethylmelamine Monohydrochloride
Pentamethylmelamine monohydrochloride

External Source Codes: 
CAS Registry Number 16268-62-5 (see NLM ChemIDplus info)
NSC Code 118742 (see NCI DTP info)
PDQ Closed Trial Search ID 39553
PDQ Open Trial Search ID 39553 (check for NCI PDQ open clinical trial info)
UMLS CUI C0070302

Other Properties:
     Name Value (qualifiers indented underneath)
code C1189
Legacy_Concept_Name Pentamethylmelamine
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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