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Version: 16.11d (Release date: 2016-11-28)
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Nilutamide (Code C1173)

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Terms & Properties

Preferred Name: Nilutamide

Definition: A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens; this agent may inhibit androgen-dependent growth of normal and neoplastic prostate cells. (NCI04)

NCI-GLOSS Definition: A drug that blocks the effects of male hormones in the body. It is a type of antiandrogen.

Display Name: Nilutamide

Label: Nilutamide

NCI Thesaurus Code: C1173 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0722107  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazoline-3,5-dione
5,5-Dimethyl-3-[4-nitro-3-(trifluoro-methyl)phenyl]-2,4-imidazolidinedione
Anandron
Nilandron
Nilutamide
NILUTAMIDE
nilutamide
RU-23908

External Source Codes: 
CAS Registry Number 63612-50-0 (see NLM ChemIDplus info)
FDA UNII Code 51G6I8B902
ChEBI ID CHEBI:7573 (see ChEBI info)
NSC Code 684588 (see NCI DTP info)
PDQ Closed Trial Search ID 40450
PDQ Open Trial Search ID 40450 (check for NCI PDQ open clinical trial info)
UMLS CUI C0722107

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Prostate cancer
Chemical_Formula C12H10F3N3O4
code C1173
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Nilutamide
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1173

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