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Version: 16.11d (Release date: 2016-11-28)
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Nandrolone Decanoate (Code C1172)

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Terms & Properties

Preferred Name: Nandrolone Decanoate

Definition: The decanoate salt form of nandrolone, an anabolic steroid analog of testosterone with androgenic, anabolic, and erythropoietin stimulating effects. Nandrolone enters the cell and binds to and activates specific nuclear androgen receptors in responsive tissue, including the prostate, seminal vesicles, scrotum, penis, larynx, hair follicles, muscle, and bone. The resulting activated hormone receptor complex translocates into the nucleus and binds to androgen response elements (ARE) in the promoter region of targeted genes, where the complex promotes gene expression necessary for maintaining male sex characteristics. Mimicking the negative feedback mechanism of testosterone, nandrolone decanoate also suppresses the secretion of luteinizing hormone (LH). Furthermore, this agent also stimulates erythropoietin production by enhancing the production of erythropoietic stimulating factors.

Label: Nandrolone Decanoate

NCI Thesaurus Code: C1172 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0068395  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Deca-Durabolin
NANDROLONE DECANOATE
Nandrolone Decanoate

External Source Codes: 
CAS Registry Number 360-70-3 (see NLM ChemIDplus info)
FDA UNII Code H45187T098
PDQ Closed Trial Search ID 42677
PDQ Open Trial Search ID 42677 (check for NCI PDQ open clinical trial info)
UMLS CUI C0068395

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Anemia of renal insufficiency; Metastatic Breast Cancer
Chemical_Formula C28H44O3
code C1172
Contributing_Source FDA
Legacy_Concept_Name Nandrolone_Decanoate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1172

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