skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Nabilone (Code C1171)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Nabilone

Definition: A synthetic cannabinoid and dibenzopyrane derivative with anti-emetic activity. Although the mechanism of action has not been fully elucidated yet, it has been suggested that nabilone is a highly selective and strong agonist for the cannabinoid receptors CB1 and CB2, both of which are coupled to Gi/o proteins. The CB1 receptors are expressed predominantly in central and peripheral neurons and receptor stimulation has been implicated in the reduction of chemotherapy-induced nausea.

Label: Nabilone

NCI Thesaurus Code: C1171 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1263104  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Cesamet
Cpd 109514
NABILONE
Nabilone

External Source Codes: 
CAS Registry Number 51022-71-0 (see NLM ChemIDplus info)
FDA UNII Code 2N4O9L084N
PDQ Closed Trial Search ID 39760
PDQ Open Trial Search ID 39760 (check for NCI PDQ open clinical trial info)
UMLS CUI C1263104

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C24H36O3
code C1171
Contributing_Source FDA
Legacy_Concept_Name Nabilone
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1171

Mainbox Bottom