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Version: 17.06d (Release date: 2017-06-26)
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N-Methylformamide (Code C1163)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: N-Methylformamide

Definition: A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. (NCI04)

Label: N-Methylformamide

NCI Thesaurus Code: C1163 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0066373  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
EK 7011
Formamide, N-methyl
formylmethylamine
Monomethylformamide
monomethylformamide
N-Methylformamide
N-METHYLFORMAMIDE
NMF
X 188

External Source Codes: 
CAS Registry Number 123-39-7 (see NLM ChemIDplus info)
FDA UNII Code XPE4G7Y986
ChEBI ID CHEBI:7438 (see ChEBI info)
NSC Code 3051 (see NCI DTP info)
PDQ Closed Trial Search ID 39511
PDQ Open Trial Search ID 39511 (check for NCI PDQ open clinical trial info)
UMLS CUI C0066373

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C2H5NO
code C1163
Contributing_Source FDA
Legacy_Concept_Name N-Methylformamide
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1163

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