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Version: 17.06d (Release date: 2017-06-26)
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Meropenem (Code C1160)

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Terms & Properties

Preferred Name: Meropenem

Definition: A broad-spectrum carbapenem with antibacterial properties, synthetic Meropenem inhibits cell wall synthesis in gram-positive and gram-negative bacteria. It penetrates cell walls and binds to penicillin-binding protein targets. Meropenem acts against aerobes and anaerobes including Klebsiella, E. coli, Enterococcus, Clostridium sp.. (NCI04)

Label: Meropenem

NCI Thesaurus Code: C1160 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0066005  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Meropenem Trihydrate
Merrem I.V.

External Source Codes: 
CAS Registry Number 119478-56-7 (see NLM ChemIDplus info)
ChEBI ID CHEBI:6770 (see ChEBI info)
PDQ Closed Trial Search ID 41899
PDQ Open Trial Search ID 41899 (check for NCI PDQ open clinical trial info)
UMLS CUI C0066005

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Gram positive and gram-negative intra-abdominal infections; bacterial meningitis
Chemical_Formula C17H25N3O5S.3H2O
code C1160
Contributing_Source FDA
Legacy_Concept_Name Meropenem
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  


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