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Version: 17.12d (Release date: 2017-12-26)
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Ex Vivo-activated Autologous Lymph Node Lymphocytes (Code C114985)

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Terms & Properties

Preferred Name: Ex Vivo-activated Autologous Lymph Node Lymphocytes

Definition: Autologous human lymph node T-lymphocytes, with potential immunostimulatory and antineoplastic activity. Upon collection of immune cells from the tumor-draining lymph node, the human lymph node lymphocytes are activated with anti-CD3/anti-CD28 microbeads, cultured with recombinant, human interleukin-2 (IL-2), expanded and isolated ex vivo. Upon reintroduction into the patient, the ex vivo-activated autologous lymph node lymphocytes recognize and lyse the tumor cells.

Label: Ex Vivo-activated Autologous Lymph Node Lymphocytes

NCI Thesaurus Code: C114985 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL472580  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Ex Vivo-activated Autologous Lymph Node Lymphocytes
X-ACT Autologous Lymph Node Lymphocytes

External Source Codes: 
PDQ Closed Trial Search ID 759605
PDQ Open Trial Search ID 759605 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C114985
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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