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Version: 17.06d (Release date: 2017-06-26)
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NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine (Code C114380)

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Terms & Properties

Preferred Name: NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine

Definition: A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a peptide derived from the tumor associated antigen human cancer-testis antigen NY-ESO-1 (NY-ESO-1(157-165)), with potential immunostimulatory and antineoplastic activities. Upon administration, the NY-ESO-1(157-165) peptide-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount both an anti-tumoral cytotoxic T-lymphocyte (CTL)- and an antibody-mediated immune response against NY-ESO-1-expressing tumor cells, which may result in tumor cell lysis. NY-ESO-1 is expressed both in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival.

Display Name: NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine

Label: NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine

NCI Thesaurus Code: C114380 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL471814  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Autologous NY-ESO-1 (157-165) Peptide-pulsed DC Vaccine
NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 758472
PDQ Open Trial Search ID 758472 (check for NCI PDQ open clinical trial info)
NCI META CUI CL471814

Other Properties:
     Name Value (qualifiers indented underneath)
code C114380
Contributing_Source CTRP
Semantic_Type Cell
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C114380

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