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Version: 17.06d (Release date: 2017-06-26)
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Keyhole Limpet Hemocyanin (Code C1139)

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Terms & Properties

Preferred Name: Keyhole Limpet Hemocyanin

Definition: A natural protein isolated from the marine mollusc keyhole limpet. Keyhole limpet hemocyanin is an immunogenic carrier protein that, in vivo, increases antigenic immune responses to haptens and other weak antigens such as idiotype proteins. (NCI04)

NCI-GLOSS Definition: A substance taken from a marine organism that may be linked to a specific antigen to boost the immune response to that antigen. KLH is being studied as a way to increase the immune response to cancer vaccines. It is a type of immune modulator.

Display Name: Keyhole Limpet Hemocyanin

Label: Keyhole Limpet Hemocyanin

NCI Thesaurus Code: C1139 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0064332  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Keyhole Limpet Hemocyanin
keyhole limpet hemocyanin
KEYHOLE LIMPET HEMOCYANIN
KLH

External Source Codes: 
FDA UNII Code FV4Y0JO2CX
NSC Code 713762 (see NCI DTP info)
PDQ Closed Trial Search ID 41836
PDQ Open Trial Search ID 41836 (check for NCI PDQ open clinical trial info)
UMLS CUI C0064332

Other Properties:
     Name Value (qualifiers indented underneath)
code C1139
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Keyhole_Limpet_Hemocyanin
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1139

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