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Version: 17.06d (Release date: 2017-06-26)
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Oxidized Avidin (Code C113800)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Oxidized Avidin

Definition: An oxidized form of the glycoprotein avidin, that can be used as a linking agent for tissue-pretargeted radionuclide therapy. Upon intralesional administration, the aldehyde groups of oxidized avidin strongly bind to the amino groups on tissue proteins, via the formation of Schiff bases. As avidin is able to strongly bind to biotin, intravenous administration of radiolabeled biotin may lead to the selective eradication of the pre-targeted tumor cells.

Label: Oxidized Avidin

NCI Thesaurus Code: C113800 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL471781  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AvidinOX
Oxidized Avidin

External Source Codes: 
PDQ Closed Trial Search ID 757657
PDQ Open Trial Search ID 757657 (check for NCI PDQ open clinical trial info)
NCI META CUI CL471781

Other Properties:
     Name Value (qualifiers indented underneath)
code C113800
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C113800

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