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Version: 17.06d (Release date: 2017-06-26)
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Folate Binding Protein J65 Peptide Vaccine (Code C113660)

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Terms & Properties

Preferred Name: Folate Binding Protein J65 Peptide Vaccine

Definition: A cancer vaccine comprised of human leukocyte antigen (HLA)-A2-restricted folate binding protein (FBP) epitope J65 (9 amino acids; EIWTFSTKV), with potential immunostimulatory and antineoplastic activities. Upon intradermal injection, FBP J65 peptide vaccine may induce a specific cytotoxic T-lymphocyte (CTL) response against J65 FBP-expressing tumor cell types. FBP is a membrane-bound, tumor-associated antigen overexpressed in various tumor types, including breast, ovarian and endometrial cancers. J65 is a strongly immunogenic peptide.

Label: Folate Binding Protein J65 Peptide Vaccine

NCI Thesaurus Code: C113660 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL458373  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
FBP J65 Peptide Vaccine
Folate Binding Protein J65 Peptide Vaccine
J65 Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 732482
PDQ Open Trial Search ID 732482 (check for NCI PDQ open clinical trial info)
NCI META CUI CL458373

Other Properties:
     Name Value (qualifiers indented underneath)
code C113660
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C113660

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