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Version: 17.06d (Release date: 2017-06-26)
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Hydrazine Sulfate (Code C1129)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Hydrazine Sulfate

Definition: The synthetic sulfate salt of hydrazine, a derivative of ammonia. Hydrazine inhibits the enzyme phosphoenol pyruvate carboxykinase, thereby blocking gluconeogenesis. This agent has been reported to decrease the excessive energy needs and cachexia of cancer patients. Classified as a likely human carcinogen, hydrazine sulfate is also a weak inhibitor of mono-amine oxidase (MAO). (NCI04)

NCI-GLOSS Definition: A substance that has been studied as a treatment for cancer and as a treatment for cachexia (body wasting) associated with advanced cancer.

Label: Hydrazine Sulfate

NCI Thesaurus Code: C1129 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0063067  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
hydrazine sulfate
Hydrazine Sulfate
HYDRAZINE SULFATE
Sehydrin

External Source Codes: 
CAS Registry Number 10034-93-2 (see NLM ChemIDplus info)
FDA UNII Code 1N369SAT01
NSC Code 150014 (see NCI DTP info)
NSC Code 215190 (see NCI DTP info)
PDQ Closed Trial Search ID 40141
PDQ Open Trial Search ID 40141 (check for NCI PDQ open clinical trial info)
UMLS CUI C0063067

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula H2O4S.H4N2
code C1129
Contributing_Source FDA
Legacy_Concept_Name Hydrazine_Sulfate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1129

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