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Version: 17.06d (Release date: 2017-06-26)
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Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877 (Code C112205)

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Terms & Properties

Preferred Name: Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877

Definition: A pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. Pan-FGFR kinase inhibitor BAY1163877 inhibits the activities of FGFRs, which may result in the inhibition of both tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. FGFRs are a family of receptor tyrosine kinases, which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival.

Display Name: Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877

Label: Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877

NCI Thesaurus Code: C112205 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL454405  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Pan-FGFR Tyrosine Kinase Inhibitor BAY1163877

External Source Codes: 
PDQ Closed Trial Search ID 754526
PDQ Open Trial Search ID 754526 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C112205
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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