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Version: 17.06d (Release date: 2017-06-26)
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Sorghum bicolor Supplement (Code C111681)

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Terms & Properties

Preferred Name: Sorghum bicolor Supplement

Definition: An herbal-based nutritional supplement containing the leaf sheaths of the plant Sorghum bicolor, with potential antioxidant, anti-inflammatory, chemopreventive and immunomodulating activities. Sorghum bicolor supplement contains various phytochemicals, including phenolic acids and polyphenols such as proanthocyanidins. Sorghum bicolor supplement is particularly rich in 3-deoxyanthocyanins, such as luteolinidin and apigeninidin, and appears to induce apoptosis and inhibit cell proliferation in cancer cells through the stimulation of various apoptosis promoter genes and the downregulation of certain apoptosis inhibitor genes. In addition, due to the strong antioxidant nature of the phytochemicals, these compounds are able to scavenge free radicals and prevent tissue damage. Also, intake of this supplement modulates the immune system by both increasing the activity of natural killer (NK) cells and initiating the activation of macrophages.

Label: Sorghum bicolor Supplement

NCI Thesaurus Code: C111681 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL454073  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Jobelyn
Sorghum bicolor Extract
Sorghum bicolor Supplement

External Source Codes: 
PDQ Closed Trial Search ID 752436
PDQ Open Trial Search ID 752436 (check for NCI PDQ open clinical trial info)
NCI META CUI CL454073

Other Properties:
     Name Value (qualifiers indented underneath)
code C111681
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C111681

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