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Version: 17.06d (Release date: 2017-06-26)
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Gallium Nitrate (Code C1109)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Gallium Nitrate

Definition: A hydrated nitrate salt of the group IIIa element gallium with potential use in the treatment of malignancy-associated hypercalcemia. Gallium nitrate localizes preferentially to areas of bone resorption and remodeling and inhibits osteoclast-mediated resorption by enhancing hydroxyapatite crystallization and reduction of bone mineral solubility. This agent also increases calcium and phosphorous deposition into bone and may increase collagen synthesis. (NCI04)

NCI-GLOSS Definition: A drug that lowers blood calcium. Used as treatment for hypercalcemia (too much calcium in the blood) and for cancer that has spread to the bone (bone metastases).

Label: Gallium Nitrate

NCI Thesaurus Code: C1109 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0061008  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
GALLIUM NITRATE
Gallium nitrate
gallium nitrate
Gallium Nitrate
GaN
Ganite
WR-135675

External Source Codes: 
CAS Registry Number 135886-70-3 (see NLM ChemIDplus info)
FDA UNII Code VRA0C6810N
NSC Code 15200 (see NCI DTP info)
PDQ Closed Trial Search ID 39249
PDQ Open Trial Search ID 39249 (check for NCI PDQ open clinical trial info)
UMLS CUI C0061008

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula Ga.3NO3.9H2O
code C1109
Contributing_Source FDA
Legacy_Concept_Name Gallium_Nitrate
Semantic_Type Inorganic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: Yes  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1109

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