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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Gabapentin (Code C1108)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Gabapentin

Definition: A synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown, gabapentin appears to inhibit excitatory neuron activity. This agent also exhibits analgesic properties. (NCI04)

NCI-GLOSS Definition: A substance that is being studied as a treatment for relieving hot flashes in women with breast cancer. It belongs to the family of drugs called anticonvulsants.

Display Name: Gabapentin

Label: Gabapentin

NCI Thesaurus Code: C1108 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0060926  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1-(aminomethyl)cyclohexaneacetic Acid

External Source Codes: 
CAS Registry Number 60142-96-3 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 38402
PDQ Open Trial Search ID 38402 (check for NCI PDQ open clinical trial info)
UMLS CUI C0060926

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Management of Epilepsy; Pain; Mania; Depression and Anxiety Disorders; Postherpetic Neuralgia
Chemical_Formula C9H17NO2
code C1108
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Gabapentin
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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