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Version: 17.12d (Release date: 2017-12-26)
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Cefixime (Code C1100)

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Terms & Properties

Preferred Name: Cefixime

Definition: A broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins.

NCI-GLOSS Definition: An antibiotic drug used to treat infection. It belongs to the family of drugs called cephalosporins.

Display Name: Cefixime

Label: Cefixime

NCI Thesaurus Code: C1100 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0060400  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
FK 027

External Source Codes: 
CAS Registry Number 79350-37-1 (see NLM ChemIDplus info)
FDA UNII Code 97I1C92E55
ChEBI ID CHEBI:472657 (see ChEBI info)
PDQ Closed Trial Search ID 37809
PDQ Open Trial Search ID 37809 (check for NCI PDQ open clinical trial info)
UMLS CUI C0060400

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H15N5O7S2.3H2O
code C1100
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Cefixime
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  


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