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Version: 17.06d (Release date: 2017-06-26)
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Etanidazole (Code C1092)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Etanidazole

Definition: A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. (NCI04)

NCI-GLOSS Definition: A drug that increases the effectiveness of radiation therapy.

Display Name: Etanidazole

Label: Etanidazole

NCI Thesaurus Code: C1092 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0059682  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-
2-Nitroimidazole-1-acetamide, N-(2-hydroxyethyl)-
Etanidazole
etanidazole
ETANIDAZOLE
SR-2508

External Source Codes: 
CAS Registry Number 22668-01-5 (see NLM ChemIDplus info)
FDA UNII Code 30DKA3Q1HL
NSC Code 301467 (see NCI DTP info)
PDQ Closed Trial Search ID 39446
PDQ Open Trial Search ID 39446 (check for NCI PDQ open clinical trial info)
UMLS CUI C0059682

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C7H10N4O4
code C1092
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Etanidazole
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: Yes  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1092

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