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Version: 17.06d (Release date: 2017-06-26)
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Liposomal Rhenium Re 186 (Code C107679)

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Terms & Properties

Preferred Name: Liposomal Rhenium Re 186

Definition: A therapeutic preparation consisting of the beta-emitting radioisotope rhenium Re 186 encapsulated in a nanoliposome, with potential antineoplastic activity. Upon intratumoral infusion of liposomal rhenium Re 186, the radioisotope releases radiation, which directly kills the tumor cells. The nanoliposomes facilitate the retention of the radioisotope by the tumor cells and localize the radiocytotoxicity to the tumor while sparing surrounding normal, healthy cells. Re-186 has a short half-life and a short path length, which contributes further to limiting the radiotoxicity to the tumor cells.

Label: Liposomal Rhenium Re 186

NCI Thesaurus Code: C107679 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL451869  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Liposomal Rhenium-186
Liposomal Rhenium Re 186
Rhenium-186 Liposome

External Source Codes: 
PDQ Closed Trial Search ID 751420
PDQ Open Trial Search ID 751420 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C107679
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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